Hu7691 free base NEW
Price | $293 | $722 | $987 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-12 |
Product Details
Product Name: Hu7691 free base | CAS No.: 2241232-43-7 |
Purity: 98.89% | Supply Ability: 10g |
Release date: 2024/11/12 |
Product Introduction
Bioactivity
名稱 | Hu7691 free base |
描述 | Hu7691 free base is an orally active, potent, and selective Akt inhibitor with anti-proliferative and neurogenic effects on various neuroblastoma cell lines. It inhibits Akt1, Akt2, and Akt3, and induces differentiation of neuroblastoma cells. |
體外活性 | In HaCaT cells, Hu7691 free base (2.25, 4.5, 9, 18, 36 μM; 24 hours) effectively induces a decrease in the phosphorylation level of Akt (S473)[1]. |
體內(nèi)活性 | In Balb/c mice (nu/nu, female, 3-4 weeks old, 20-25 g), Hu7691 free base (12.5, 25, 50 mg/kg; oral; once daily for 22 days) exhibited dose-dependent inhibition of tumor growth[1]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
關(guān)鍵字 | Hu7691 free base | Hu-7691 free base | Hu7691 |
相關(guān)產(chǎn)品 | Ethyl gallate | Oridonin | Capivasertib | SKLB-163 | Scutellarin | Artemisinin | Honokiol | 2,3-Butanediol | MK-2206 dihydrochloride | AKT Kinase Inhibitor |
相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 抗衰老化合物庫(kù) | 已知活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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