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Postion:Product Catalog >HQ461
HQ461
  • HQ461

HQ461 NEW

Price $38 $54 $89
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: HQ461 CAS No.: 1226443-41-9
Purity: 98.11% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameHQ461
DescriptionHQ461 is a molecular glue that promotes CDK12-DDB1 interaction, triggering cyclin K degradation, decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 62 mg/mL (179.48 mM), Sonication and heating to 60℃ are recommended.
KeywordsHQ461 | cyclin K degrader | Cyclin dependent kinase | molecular glue | HQ-461 | HQ 461 | CDK12 substrate phosphorylation | inhibit | CDK | Inhibitor | Molecular Glues | DNA damage
Inhibitors RelatedThalidomide | Lenalidomide | Abemaciclib
Related Compound LibrariesBioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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