HPPH NEW
Price | $60 | $147 | $263 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: HPPH | CAS No.: 149402-51-7 |
Purity: 99.72% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱(chēng) | HPPH |
描述 | HPPH (Photochlor) (Photochlor) is a second-generation photosensitizer. It is used as photodynamic therapy (PDT) agent. |
體外活性 | Cells treated with GO-PEG-HHPH displays a stronger fluorescence signal than those treated with free HPPH. In fact, the fluorescence of HPPH is rather weak. After 24 h, Fluorescence image of 4T1 cells incubated with 0.49 μg/mL GO-PEG, 1 μM HPPH (free HPPH), or equivalent amount of GO-PEG-HPPH (1 μM HPPH and 0.49 μg/mL GO-PEG). The cellular uptake of GO-PEG-HPPH and HPPH is investigated with 4T1 murine mammary cancer cells. The cells are incubated with GO-PEG-HPPH and free HPPH at equivalent HPPH concentration (1 μM) for 24 h and then observed with a confocal microscope [1]. |
體內(nèi)活性 | A combination treatment regimen for Colo26-HA tumor-bearing BALB/c mice involves administering an HPPH-PDT (0.4 μmoles/kg HPPH followed by 665 nm light at 48 J/cm2) to enhance anti-tumor immunity. Following a 9-day rest period and an HPPH injection, tumors receive a control treatment with 665 nm light at 132 J/cm2 on day 10 [2]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (78.52 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
關(guān)鍵字 | HPPH | Inhibitor | inhibit |
相關(guān)庫(kù) | 抗肺癌化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 抗癌臨床化合物庫(kù) | 藥物功能重定位化合物庫(kù) | NO PAINS 化合物庫(kù) | 臨床期小分子藥物庫(kù) | 已知活性化合物庫(kù) | 抗癌化合物庫(kù) | 抗癌活性化合物庫(kù) | 抗癌藥物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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