Homatropine Methylbromide NEW
| Price | $36 | $46 | $59 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Homatropine Methylbromide | CAS No.: 80-49-9 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Homatropine Methylbromide |
| Description | Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties. |
| In vitro | Homatropine [14C]methylbromide administered rectally in rats achieved higher and quicker peak plasma concentrations compared to other routes. After 12 hours, 28% of the [14C] was excreted in the urine, with 56% remaining in the colon. Unlabeled homatropine methylbromide, delivered via a rectal suppository in anesthetized rats, rapidly blocked the effects of the vagus nerve on heart rate and of intravenous acetylcholine on blood pressure. A dose of 20 mg/kg homatropine increased the survival rate to 30% in rats poisoned with diazinon, with death occurring between 4 to 12 minutes, whereas a 10 mg/kg dose was ineffective in preventing mortality. |
| In vivo | When combined with hexamethonium, 20 μM Homatropine yields only a dose ratio of 95.0 in guinea pig atria. In contrast, 20 μM Homatropine alone produces a dose ratio of 259 in guinea pig atria. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (135.03 mM) Ethanol : 10 mg/mL (27.0 mM) H2O : 68 mg/mL (183.6 mM) |
| Keywords | Inhibitor | Muscarinic acetylcholine receptor | mAChR | Homatropine Methylbromide | inhibit |
| Inhibitors Related | Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Choline chloride | Propoxur |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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