HDAC6-IN-11 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: HDAC6-IN-11 | CAS No.: 2409072-27-9 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | HDAC6-IN-11 |
| Description | HDAC6-IN-11 (Compound 9) is a selective HDAC6 inhibitor with an IC50 value of 20.7 nM, demonstrating over 300-fold selectivity against other isoforms [1], and exhibits anti-proliferative activities against cancer cells. |
| In vitro | HDAC6-IN-11 treatment, at concentrations ranging from 0.44-6.68 μM over 48 hours, exhibits anti-proliferative effects on A549 and HCT116 cells, reducing their proliferation rates with half-maximal inhibitory concentrations (GI50) of 3.2 μM for A549 cells and 1.82 μM for HCT116 cells, respectively [1]. Additionally, exposure to HDAC6-IN-11 across a broader concentration span of 0-20 μM for the same duration enhances the acetylation of H3 and tubulin in HCT116 cells, demonstrating a dose-dependent elevation in the acetylation levels of these proteins and notably increasing acetylated tubulin [1]. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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