Halofuginone hydrobromide NEW
| Price | $31 | $44 | $72 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Halofuginone hydrobromide | CAS No.: 64924-67-0 |
| Purity: 98.5% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Halofuginone hydrobromide |
| Description | Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 12 mg/mL (24.21 mM), Sonication is recommended. |
| Keywords | type-I | RU-19110 | Parasite | Na channels | DNA/RNA Synthesis | Calcium Channel | collagen | collagen-1 | prolyl-tRNA | Halofuginone hydrobromide | Inhibitor | RU19110 | Halofuginone | inhibit | Na+ channels | RU 19110 | osteoarthritis | TGF-β | Ca2+ channels | TGF-beta/Smad | Halofuginone Hydrobromide | Ca channels | Transforming growth factor beta | Sodium Channel |
| Inhibitors Related | 5-Fluorouracil | Phenytoin sodium | Kaempferol | Kojic acid | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Metronidazole | Doxycycline | Valproic Acid | Lidocaine hydrochloride | Thymidine |
| Related Compound Libraries | Anti-Parasitic Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Neuroprotective Compound Library | Inhibitor Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | TGF-beta/Smad Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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