Guanidine isothiocyanate, 593-84-0 , also known as Tris, Guanidine isothiocyanate is a well-known biological buffer. In addition,  is also used to prepare surfactants, vulcanization accelerators and intermediates of some drugs, and can also be used as pharmaceutical excipients, cosmetic additives, decoration coatings, etc.

Main application areas:

denaturing and splitting cells; 

RNA and DNA were extracted. No RNA and DNA enzyme activity

TRIzol is a new total RNA extraction reagent, which can directly extract total RNA from cells or tissues. It contains phenol, guanidine isothiocyanate and other substances, which can quickly break cells and inhibit nuclease released by cells.