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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Guanethidine
Guanethidine
  • Guanethidine

Guanethidine NEW

Price Get Latest Price
Package 100mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Guanethidine CAS No.: 55-65-2
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameGuanethidine
DescriptionGuanethidine sulphate, synthesized in 1959, is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.
In vitroSympathetic fibers ablation is associated with a loss of rat endothelial cell marker (RECA), but no significant effect of guanethidine was found on the survival of endothelial cells and mesenchymal stem cells in vitro [1].
In vivoGuanethidine (30 mg/kg, s.c., 1 h) administration does not alter IL-18 induced hypernociception in TNFR1 (-/-) mice, indicating that this sympathetic blocker is ineffective in this context [2]. This outcome was observed in a study involving WT Balb/c, TNFR1 (-/-), and IFN-γ (-/-) mice, with guanethidine diluted in saline.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Keywords1 [2 (azocan 1 yl)ethyl]guanidine | Guanethidine | 1[2(azocan1yl)ethyl]guanidine

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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