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Postion:Product Catalog >API>Respiratory Drugs>Expectorants>Guaifenesin
Guaifenesin
  • Guaifenesin

Guaifenesin NEW

Price $29
Package 1mL
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-05

Product Details

Product Name: Guaifenesin CAS No.: 93-14-1
Purity: 99.69% Supply Ability: 10g
Release date: 2024/11/05

Product Introduction

Bioactivity

名稱Guaifenesin
描述Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.
體內(nèi)活性Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) produces effective and safe surgical anesthesia for over 30 minutes in New Zealand white rabbits. Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) mildly depresses respiratory rate but heart rate and arterial blood pressure are not significantly affected. Guaifenesin (200 mg/kg, intravenously) is combined with sodium pentobarbital (20 mg/kg, intravenously) to produce surgical anesthesia for a period of more than 30 minutes. [1] Guaifenesin (50 mg/mL) combined Xylazine (0.1 mg/mL) and Ketamine (1.0 mg/mL) results in excellent anesthetic induction and maintenance with cardiopulmonary alterations similar to those associated with isoflurane in mechanically ventilated calves. [2] Guaifenesin (150 mg/kg) decreases spectral edge frequency (SEF) and total power in pigs. [3] Guaifenesin prevents adverse anesthetic induction events caused by Propofol in horse. Guaifenesin (90 mg/kg) followed by Propofol (3 mg/kg) should be sufficient to immobilize > 99% of calm healthy adult horses. [4] Guaifenesin (100 mg/kg) produces moderate behavioral changes in the social conflict test in mice. Guaifenesin (200 mg/kg) combined with Paracetamol (200 mg/kg) causes significantly more pronounced analgesic effects that the corresponding doses of paracetamol alone in mice. [5]
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 50 mg/mL (252.24 mM)
H2O : 23 mg/mL (116 mM)
Ethanol : 38 mg/mL (191.7 mM)
關(guān)鍵字sputum | officinale | Guajacum | cough | narcotic | inhibit | expectorant | Inhibitor | Guaifenesin | Linné
相關(guān)庫(kù)經(jīng)典已知活性庫(kù) | 中藥單體化合物庫(kù) | 植物來源化合物庫(kù) | 天然產(chǎn)物庫(kù) | 藥物功能重定位化合物庫(kù) | 高通量篩選天然產(chǎn)物庫(kù) | FDA 上市藥物庫(kù) | 抗感染天然產(chǎn)物庫(kù) | 已知活性化合物庫(kù) | 藥食同源庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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