成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >GSK872 HCl(1346546-69-7 free base)
GSK872 HCl(1346546-69-7 free base)
  • GSK872 HCl(1346546-69-7 free base)

GSK872 HCl(1346546-69-7 free base) NEW

Price $31 $72 $122
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: GSK872 HCl(1346546-69-7 free base) CAS No.: 2703752-81-0
Purity: 99% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱GSK872 HCl(1346546-69-7 free base)
描述GSK872 HCl(1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
體外活性GSK872 (1 μM) has no inhibition for most of 300 human protein kinases tested. It fails to inhibit RIP1 kinase. In HT-29 cells, GSK872 concentration-dependently blocks TNF-induced necroptosis. In cell-based assays, there is a 100- to 1000-fold shift in the IC50 compared to the cell-free biochemical assays. GSK872 inhibits DAI- or TLR3-induced (RIP1-independent) death. It induces caspase activation and then induces apoptotic cell death[1].
體內(nèi)活性In compared with no treatment after ischemic injury in vivo, GSK872 can significantly reduce HIF-1α expression [3].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (260.76 mM)
關(guān)鍵字GSK872 HCl(1346546697 free base) | GSK-872 HCl(1346546-69-7 free base) | GSK872 HCl(1346546 69 7 free base) | GSK872 HCl | 1346546-69-7 free base | 1346546-69-7
相關(guān)產(chǎn)品PK68 | Necrostatin-1 | RIPK2-IN-5 | Oditrasertib | LY-364947 | Necroptosis-IN-1 | ICCB-19 hydrochloride | RIPK1-IN-9 | Necrostatin-34 | RIPA-56 | GSK2983559 free acid | Zharp2-1
相關(guān)庫經(jīng)典已知活性庫 | 激酶抑制劑庫 | 細(xì)胞焦亡化合物庫 | 抑制劑庫 | 抗前列腺癌化合物庫 | NO PAINS 化合物庫 | 腫瘤免疫治療小分子化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$96.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
$0.00/1kg
VIP6Y
Zison Pharmaceutical (Shandong) Co., Ltd.
2024-05-24
$102.00/1kg
VIP2Y
Wuhan Quanjinci New Material Co.,Ltd.
2023-10-24
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY