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Postion:Product Catalog >GSK2801
GSK2801
  • GSK2801

GSK2801 NEW

Price $36 $47 $108
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-05

Product Details

Product Name: GSK2801 CAS No.: 1619994-68-1
Purity: 99.88% Supply Ability: 10g
Release date: 2024/11/05

Product Introduction

Bioactivity

名稱GSK2801
描述GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.
體外活性In U2OS cells transfected with mutant BAZ2A (N1873F), GSK2801 (1 μM) accelerates FRAP half-recovery time by displacing BAZ2A from chromatin. [1]
體內(nèi)活性In male CD1 mice, GSK2801 (30 mg/kg, p.o. and i.p.) has reasonable in vivo exposure after oral dosing, modest clearance, and reasonable plasma stability. [1]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 18.6 mg/mL (50 mM)
關(guān)鍵字GSK2801 | inhibit | GSK 2801 | Inhibitor | TNBC | BAZ2A | Epigenetic Reader Domain | Apoptosis | GSK-2801 | BAZ2B | cetyl-lysine | orally
相關(guān)產(chǎn)品Stavudine | 5-Fluorouracil | Acetylcysteine | Kaempferol | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Curcumin
相關(guān)庫細胞凋亡化合物庫 | 細胞重編程化合物庫 | 經(jīng)典已知活性庫 | 染色質(zhì)修飾分子庫 | 抑制劑庫 | NO PAINS 化合物庫 | 口服活性化合物庫 | PPI抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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