Gomisin J NEW
Price | $35 | $73 | $119 |
Package | 2mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-05 |
Product Details
Product Name: Gomisin J | CAS No.: 66280-25-9 |
Purity: 99.69% | Supply Ability: 10g |
Release date: 2024/11/05 |
Product Introduction
Bioactivity
名稱 | Gomisin J |
描述 | Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. |
體外活性 | Gomisin J attenuated lipid accumulation in OA-induced HepG2 cells.?It also suppressed the expression of lipogenic enzymes and inflammatory mediators and increased the expression of lipolytic enzymes in OA-induced HepG2 cells.?Furthermore, the use of specific inhibitors and fetuin-A siRNA and liver kinase B1 (LKB1) siRNA transfected cells demonstrated that gomisin J regulated lipogenesis and lipolysis via inhibition of fetuin-A and activation of an AMP-activated protein kinase (AMPK)-dependent pathway in HepG2 cells[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (128.71 mM) |
關鍵字 | Ca channels | Ca2+ channels | Inhibitor | AMPK | AMP-activated protein kinase | inhibit | Gomisin J | Calcium Channel |
相關產品 | Nisoldipine | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Adenosine monophosphate | Adenosine 5'-monophosphate monohydrate | Methyl cinnamate | Ethyl cinnamate | Metformin hydrochloride | 1-Octanol | 2-Nitrobenzoic acid | Chitosan oligosaccharide |
相關庫 | 抗癌天然產物庫 | 疼痛相關化合物庫 | 中藥單體化合物庫 | 激酶抑制劑庫 | 天然產物庫 | 神經保護化合物庫 | 高通量篩選天然產物庫 | 抗衰老化合物庫 | 離子通道庫 | 古代經典名方目錄分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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