Product Details
Product Name:
GN44028 |
CAS No.:
1421448-26-1 |
Purity:
98.20% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | GN44028 |
Description | GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. However, It can not be suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 44 mg/mL (144.11 mM)
|
Keywords | colorectal cancer | HIFs | Hypoxia | HeLa | ME23 | GSCs | GN44028 | GN 44028 | HIF/HIF Prolyl-Hydroxylase | inhibit | HCT116 | cancer | heterodimerization | HIF-PH | Hypoxia-inducible factors | GN-44028 | PN12 | Inhibitor |
Inhibitors Related | M1002 | Dapagliflozin | ZINC13466751 | DMOG | PT-2385 | Roxadustat | Hydroxycitric acid tripotassium hydrate | Pantoprazole sodium | Oltipraz | Vadadustat | Acriflavine Hydrochloride | Cinnamaldehyde |
Related Compound Libraries | Glycolysis Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Anti-Cancer Metabolism Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |