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Postion:Product Catalog >Gemigliptin Tartrate(911637-19-9 free base)
Gemigliptin Tartrate(911637-19-9 free base)
  • Gemigliptin Tartrate(911637-19-9 free base)

Gemigliptin Tartrate(911637-19-9 free base) NEW

Price $34 $55 $89
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: Gemigliptin Tartrate(911637-19-9 free base) CAS No.: 1374639-74-3
Purity: 98% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱Gemigliptin Tartrate(911637-19-9 free base)
描述Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
體外活性Gemigliptin tartrate inhibits the formation of AGE-BSA with IC50 of 11.69 mM[1]. Gemigliptin tartrate suppresses the cross-linking of preformed AGE-BSA with rat tail tendon collagen with an IC50 of 1.39 mM[1]. Gemigliptin tartrate is a competitive DPP-4 inhibitor with a Ki of 7.25 nM[2].
體內(nèi)活性Gemigliptin tartrate inhibits AGEs formation and AGE cross-links in vivo[1]. Gemigliptin tartrate dose-dependently inhibits plasma DPP-4 activity in rats, dogs, and monkeys[2].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 90 mg/mL (140.75 mM), Sonication is recommended.
關(guān)鍵字type | Gemigliptin | products | mellitus | peptidase-4 | Gemigliptin Tartrate(911637 19 9 free base) | dipeptidyl | Gemigliptin Tartrate(911637199 free base) | advanced | Gemigliptin Tartrate(911637-19-9 free base) | diabetes | Inhibitor | LC15-0444 Tartrate | end | glycation | DPP | Dipeptidyl Peptidase | LC15-0444 | AGE | inhibit
相關(guān)產(chǎn)品Sitagliptin | Vildagliptin | 4'-Hydroxychalcone
相關(guān)庫FDA上市及藥典收錄分子庫 | 經(jīng)典已知活性庫 | 上市藥物庫 | 蛋白酶抑制劑庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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$41.00/1mg
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Zison Pharmaceutical (Shandong) Co., Ltd.
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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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