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Postion:Product Catalog >API>Antineoplastic agents>Tinib Antineoplastic drugs>Gefitinib
Gefitinib
  • Gefitinib
  • Gefitinib
  • Gefitinib
  • Gefitinib
  • Gefitinib

Gefitinib NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 10000kg
Update Time: 2024-04-13

Product Details

Product Name: Gefitinib CAS No.: 184475-35-2
EC-No.: 643-034-7 Min. Order: 1kg
Purity: 99% Supply Ability: 10000kg
Release date: 2024/04/13

Manufacturer Provide API Powder Antineoplastic Iressa CAS 184475-35-2 Gefitinib

Article illustration

Introduction

Product Name: Gefitinib

Other Name :N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine                                                   Gefitinib

CAS NO:184475-35-2

Purity: 99%min
Appearance:White crystalline powder

Molecular formula:C22H24ClFN4O3

MW:446.9

Melting Pint :119-120°C

Boiling Point :586.8±50.0 °C(Predicted)

Density :1.322±0.06 g/cm3(Predicted)

Storage :Keep in dark place,Inert atmosphere,Room temperature


Gefitinib, is a drug used for certain breast, lung , and other cancers, also known as Iressa, a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, for the treatment of prior locally advanced or metastatic non-chemical treatment or unsuitable for chemotherapysmall cell lung cancer (NSCLC).

Gefitinib is the first molecular targeted drug to be used in non-small cell lung cancer treatment. Epidermal growth factors (EGF) are a kind of polypeptide with a relative molecular mass of 6.45x103, and they can bind with epidermal growth factor receptors (EGFR) on target cell membrane surfaces to trigger biological effects. EGFR is a type of tyrosine kinase (TK) type receptor, so when bound with EGF, it will promote TK activation in the receptor. This will cause tyrosine residue in the receptor to autophosphorylate and send continuous dividing signals into the cell, causing cell proliferation and differentiation. EGFR is abundant in human tissue, and it is highly expressed in malign tumors. 

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Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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