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Postion:Product Catalog >GBR 12783 dihydrochloride
GBR 12783 dihydrochloride
  • GBR 12783 dihydrochloride

GBR 12783 dihydrochloride NEW

Price $33 $46 $73
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-12

Product Details

Product Name: GBR 12783 dihydrochloride CAS No.: 67469-75-4
Purity: 97.81% Supply Ability: 10g
Release date: 2024/11/12

Product Introduction

Bioactivity

名稱GBR 12783 dihydrochloride
描述GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
體內(nèi)活性GBR 12783 (10 mg/kg;?intraperitoneal injection;?for 100 minutes;?male Sprague-Dawley rats) treatment reinforces specifically dopamine transmission only at synapses instantaneously active, increases hippocampal ACh release and improves memory performance in a passive avoidance task[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 45 mg/mL (92.69 mM)
關(guān)鍵字GBR 12783 | GBR 12783 Dihydrochloride | GBR12783 Dihydrochloride | GBR-12783 | GBR12783 | GBR-12783 Dihydrochloride
相關(guān)庫經(jīng)典已知活性庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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