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Postion:Product Catalog >API>Digestive system drugs>Antacid and Mucosal protective Drugs>Gastrin I Human
Gastrin I Human
  • Gastrin I Human

Gastrin I Human NEW

Price Get Latest Price
Package 1kg 25kg
Min. Order: 1kg
Supply Ability: 20MT
Update Time: 2024-12-23

Product Details

Product Name: Gastrin I Human CAS No.: 10047-33-3
Min. Order: 1kg Purity: 99%
Supply Ability: 20MT Release date: 2024/12/23

Gastrin is a peptide hormone produced by G cells in the stomach lining, and it plays a crucial role in regulating the digestive process in humans. Its primary function is to stimulate the secretion of gastric acid (HCl) from the parietal cells in the stomach, which aids in the breakdown of food. Here are some key applications and roles of gastrin in human physiology:

1. Stimulation of Gastric Acid Secretion

  • Gastrin binds to receptors on parietal cells, triggering the release of gastric acid. This acid helps to digest food, particularly proteins, and also assists in the activation of digestive enzymes like pepsin.

2. Regulation of Stomach Motility

  • Gastrin also helps regulate the movement of the stomach, ensuring food is mixed and churned properly. This promotes the efficient digestion and emptying of the stomach contents into the small intestine.

3. Control of Gastric Mucosal Growth

  • Gastrin has a role in promoting the growth of the gastric mucosa (lining of the stomach), which protects the stomach lining from the corrosive effects of gastric acid.

4. Involvement in the Gastrocolic Reflex

  • Gastrin plays a role in the gastrocolic reflex, which is a physiological process where food intake triggers an increase in colonic motility, helping to regulate bowel movements.

5. Pathophysiological Implications

  • Hypergastrinemia (Excess Gastrin): In some conditions, such as Zollinger-Ellison syndrome, there is excessive secretion of gastrin, leading to increased gastric acid production. This can result in ulcers in the stomach or duodenum, and in rare cases, it can lead to other gastrointestinal issues like diarrhea.

  • Hypogastrinemia (Low Gastrin): Insufficient gastrin secretion can lead to reduced gastric acid production, impairing digestion and causing symptoms like bloating, indigestion, and malabsorption of nutrients.

6. Diagnostic Applications

  • Gastrin levels can be measured in blood tests to help diagnose certain gastrointestinal disorders, including Zollinger-Ellison syndrome, gastritis, and other acid-related disorders.

  • It can also be used to assess the function of the stomach and to monitor patients who have undergone gastric surgery.

In clinical practice, gastrin measurement is particularly useful for diagnosing conditions related to abnormal acid secretion, and its therapeutic modulation can be part of the treatment for conditions such as ulcers or acid reflux.


Company Profile Introduction

Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance. With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy. At Watson Biotechnology, we pride ourselves on our cutting-edge facilities and state-of-the-art technology, which enable us to deliver superior products that cater to a diverse range of needs across various sectors. Our dedication to continuous improvement and customer satisfaction drives us to maintain stringent quality control processes and foster an environment of innovation and growth. Join us at Watson Biotechnology Co., Ltd as we continue to pioneer advancements in biotechnology and contribute to a healthier, more sustainable future.

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