gamma-DGG acetate(6729-55-1 free base) NEW
Price | $29 | $39 | $55 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: gamma-DGG acetate(6729-55-1 free base) | CAS No.: 2935387-13-4 |
Purity: 99.81% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | gamma-DGG acetate(6729-55-1 free base) |
Description | gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor. |
In vitro | gamma-DGG (γ-DGG) acetate is the most effective antagonist of the excitatory postsynaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p.gamma-DGG blocks less at higher glutamate concentration. gamma-DGG (200-400 μM) in the bath decreases the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses) and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left[1]. The quantal analysis displays that the reduction in the e.p.s.p. paralleled the reduction in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG[2]. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : 50 mg/mL (189.23 mM), Sonication is recommended. DMSO : Slightly soluble |
Keywords | gamma-DGG acetate(6729-55-1 free base) | gammaDGG acetate(6729551 free base) | gamma DGG acetate(6729 55 1 free base) | rDGG | gamma-D-Glutamylglycine | gammaDGG | r-D-Glutamylglycine |
Inhibitors Related | IDRA-21 | Decanoic Acid | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine | Memantine hydrochloride |
Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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