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Postion:Product Catalog >gamma-DGG acetate(6729-55-1 free base)
gamma-DGG acetate(6729-55-1 free base)
  • gamma-DGG acetate(6729-55-1 free base)

gamma-DGG acetate(6729-55-1 free base) NEW

Price $29 $39 $55
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: gamma-DGG acetate(6729-55-1 free base) CAS No.: 2935387-13-4
Purity: 99.81% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Namegamma-DGG acetate(6729-55-1 free base)
Descriptiongamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
In vitrogamma-DGG (γ-DGG) acetate is the most effective antagonist of the excitatory postsynaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p.gamma-DGG blocks less at higher glutamate concentration. gamma-DGG (200-400 μM) in the bath decreases the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses) and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left[1]. The quantal analysis displays that the reduction in the e.p.s.p. paralleled the reduction in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG[2].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 50 mg/mL (189.23 mM), Sonication is recommended.
DMSO : Slightly soluble
Keywordsgamma-DGG acetate(6729-55-1 free base) | gammaDGG acetate(6729551 free base) | gamma DGG acetate(6729 55 1 free base) | rDGG | gamma-D-Glutamylglycine | gammaDGG | r-D-Glutamylglycine
Inhibitors RelatedIDRA-21 | Decanoic Acid | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine | Memantine hydrochloride
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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