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Postion:Product Catalog >Inorganic chemistry>Inorganic salts>Metal halide and Halogen salt>Metal chlorides and salt>Gadolinium chloride
Gadolinium chloride
  • Gadolinium chloride

Gadolinium chloride NEW

Price $41 $53 $82
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Gadolinium chloride CAS No.: 10138-52-0
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameGadolinium chloride
DescriptionGadolinium chloride is a calcium-sensing receptor (CaSR) agonist
In vitroGadolinium chloride (GdCl ) , a well-known Kupffer/foam cell inhibitor, at late stages of NPC liver disease and compared it with NPC1 genetic rescue in hepatocytes in vivo.?GdCl treatment successfully blocked the endocytic capacity of hepatic Kupffer/foam measured by India ink endocytosis, decreased the levels CD68-A marker of Kupffer cells in the liver-and normalized the transaminase levels in serum of NPC mice to a similar extent to those obtained by genetic Npc1 rescue of liver cells.?Gadolinium salts are widely used as magnetic resonance imaging (MRI) contrasts.?This study opens the possibility of targeting foam cells with gadolinium or by other means for improving NPC liver disease.?Synopsis: Gadolinium chloride can effectively rescue some parameters of liver dysfunction in NPC mice and its potential use in patients should be carefully evaluated.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 7.5 mg/mL (28.45 mM), Sonication is recommended.
H2O : 9.85 mg/mL
KeywordsGadolinium Chloride | specific | GdCl3 | Gadolinium chloride | GdCl 3 | GdCl-3 | inhibit | calcium-sensing | CaSR | receptor | Inhibitor | H9c2 | cardiovascular | Calcium-sensing receptor | Gadolinium
Inhibitors RelatedSB-423562 | Strontium ranelate | Cinacalcet | Tecalcet Hydrochloride | NPS-2143 | Strontium chloride | Calindol hydrochloride | Cinacalcet hydrochloride | AC265347 | Evocalcet
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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