Fucoidan NEW
| Price | $46 | $128 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: Fucoidan | CAS No.: 9072-19-9 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | Fucoidan |
| 描述 | Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating. |
| 細(xì)胞實(shí)驗(yàn) | The influence of fucoidan on B16 melanoma cells and cellular tyrosinase:Cell viability was examined by the cell counting kit-8 assay. Cellular tyrosinase activity and melanin content were determined using spectrophotometric methods and protein expression was analyzed by immunoblotting. Morphological changes in B16 melanoma cells were examined by phase contrast microscopy and apoptosis was analyzed by flow cytometry[1]. |
| 動(dòng)物實(shí)驗(yàn) | In vivo, therapy experiments were conducted on Babl/c mice bearing breast cancer.?The tumor volume and weight were measured.?The number of apoptotic cells and microvascular density (MVD) in tumor tissues were assessed by TUNEL and CD34 immunostaining.?Immunohistochemical assays and ELISA assay were used to detect the expression of VEGF in tissues[2]. |
| 體外活性 | Fucoidan significantly decreased viable cell number in a dose-response manner with an IC50 of 550 ±4.3 μg/mL.?Cell morphology was altered and significant apoptosis was induced when cells were exposed to 550 μg/mL fucoidan for 48 h[1]. |
| 體內(nèi)活性 | Intraperitoneal injection of fucoidan in breast cancer models reduced the tumor volume and weight.?The enhanced antitumor efficacy was associated with decreased angiogenesis and increased induction of apoptosis[2]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 10 mM DMSO : Insoluble |
| 關(guān)鍵字 | polysaccharide | anticoagulant | diabetes | inhibit | Glucosidase | antisteatotic | Inhibitor | α-amylase | α-glucosidase. Antioxidant | Type 2 | anticancer | Fucoidan |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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