Fluvastatin sodium NEW
| Price | $30 | $44 | $63 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Fluvastatin sodium | CAS No.: 93957-55-2 |
| Purity: 99.46% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Fluvastatin sodium |
| Description | Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent. |
| In vitro | In a rabbit model, daily administration of Fluvastatin (10 mg/kg) significantly reversed the inhibition of acetylcholine-induced vasodilation, effectively reducing hyperlipidemia. |
| In vivo | In human aortic smooth muscle cells, Fluvastatin (100 nM) reduces the formation of superoxide anion radicals activated by angiotensin II. In CHL/IU cells, Fluvastatin (8 μM) offers protection against DNA damage. It significantly inhibits the formation of thiobarbituric acid-reactive substances in lipid peroxidation initiated by divalent iron ions (IC50=12 μM). Fluvastatin (1-100 μM) can inhibit lipid peroxidation mediated by peroxyl radicals induced by 2,2'-azobis(2-amidinopropane) dihydrochloride and 2,2'-azobis. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 10.8 mg/mL (25 mM) DMSO : 43.3 mg/mL (100 mM) |
| Keywords | Inhibitor | HMG-CoA Reductase (HMGCR) | Nrf2-dependent | muscle | pathway | HMG-CoA | Autophagy | smooth | inhibit | antioxidant | XU 62-320 | stress | reductase | Fluvastatin | vascular | oxidative | Fluvastatin sodium | Ferroptosis |
| Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Paeonol | L-Cystine | Naringin | Gefitinib |
| Related Compound Libraries | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Oxidation-Reduction Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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