成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >API>Antipyretic analgesics>Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)>Etodolac
Etodolac
  • Etodolac

Etodolac NEW

Price $34 $48 $68
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Etodolac CAS No.: 41340-25-4
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameEtodolac
DescriptionEtodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2.
In vitroEtodolac markedly inhibits ICl, vol activation by TNFα as well as subsequent apoptotic events such as apoptotic cell volume decrease (AVD) and elevation of caspase-3/7 activity in isolated rabbit articular chondrocytes. [1]
In vivoEtodolac attenuates paclitaxel-induced peripheral neuropathy by a COX-independent pathway in a mouse model of mechanical allodynia. [2] Etodolac and other NSAIDs inhibits paw swelling and causes gastric mucosal lesions in adjuvant arthritic rats in a dose-dependent manner. Etodolac shows the highest UD(50) value and safety index among these NSAIDs in arthritic rats. Etodolac also shows the highest UD(50) value and safety index, except when its effects are assessed by acetic acid-induced writhing in normal rats. [3] Etodolac dose-dependently inhibits the development of gastric cancer, and no cancer is detected at a dose of 30 mg/kg/day. Etodolac does not affect the extent of inflammatory cell infiltration or oxidative DNA damage, but it significantly inhibits mucosal cell proliferation and dose-dependently represses the development of intestinal metaplasia in the stomachs of Helicobacter pylori (Hp)-infected Mongolian gerbils (MGs). [4] Etodolac alleviates heat-evoked hyperalgesia in the CCI rats and the increase in number of TRAP-positive multinucleated osteoclasts on the CCI-side is abrogated, however, it does not inhibit the decrease of bone mineral content (BMC) and bone mineral density (BMD) on the CCI-side. [5]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 54 mg/mL (187.9 mM)
DMSO : 35 mg/mL (121.8 mM)
KeywordsAY24236 | inhibit | Inhibitor | Cyclooxygenase | AY 24236 | COX | Etodolac
Inhibitors RelatedIbuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | Paradol | Indomethacin sodium hydrate | Trometamol | Glafenine | Revaprazan hydrochloride
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$34.00/25mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$1.90/1KG
VIP4Y
Hebei Chuanghai Biotechnology Co,.LTD
2024-08-20
$88.00/1KG
Xiamen Wonderful Bio Technology Co., Ltd.
2023-07-21
$0.00/25KG
VIP5Y
Hebei Mojin Biotechnology Co., Ltd
2022-07-11
$19.00/1Kg/Bag
Hong Kong Tiansheng New Material Trading Co., Ltd
2022-01-10
$10.00/1Kg/Bag
Hebei Zhanyao Biotechnology Co. Ltd
2021-11-15
$15.00/1KG
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10
$1.10/1g
VIP4Y
Dideu Industries Group Limited
2021-06-15
$190.00/1KG
Baoji Guokang Healthchem co.,ltd
2021-06-03
$20.00/1KG
Longyan Tianhua Biological Technology Co., Ltd
2020-11-11
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY