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Postion:Product Catalog >ES2 peptide
ES2 peptide
  • ES2 peptide

ES2 peptide NEW

Price Get Latest Price
Package 1mg 5mg 10mg
Min. Order: 0.10000000149011612mg
Supply Ability: 20 tons
Update Time: 2024-09-25

Product Details

Product Name: ES2 peptide Min. Order: 0.10000000149011612mg
Purity: 99% min Supply Ability: 20 tons
Release date: 2024/09/25

ES2 can act as senolytics for eliminating senescent human cancer cells both in cell culture and in orthotopic mouse models. It disrupts FOXO4-TP53 foci, activates TP53 mediated apoptosis and preferentially binds FOXO4 compared to TP53. Intratumoural delivery of ES2 plus a BRAF inhibitor results in a significant increase in apoptosis and a survival advantage in mouse models of melanoma. Repeated systemic delivery of ES2 to older mice results in reduced senescent cell numbers in the liver with minimal toxicity. When compared with FOXO4-DRI peptide and found that, while FOXO4-DRI has minimal lytic activity in dividing cells, ES2 peptide had 3-7 times higher senolytic activity



Company Profile Introduction

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

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INQUIRY

+86-13627115097
market02@senwayer.com