Epieriocalyxin A NEW
Price | $216 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Epieriocalyxin A | CAS No.: 191545-24-1 |
Purity: 97.00% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Epieriocalyxin A |
Description | Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future. |
In vitro | Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. EpiA induced annexin V flipping in the cell membrane and DNA fragment. We also showed that EpiA induced the generation of ROS in cells, as well as damage of the mitochondrial membrane. Western blot results showed that both JNK and ERK1/2 activation was decreased after EpiA treatment in a dose-dependent manner. EpiA increased the expression of caspase 3 and Bax and decreased Bcl2 expression. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | diterpenoid | Extracellular signal regulated kinases | colon cancer | ERK1/2 | JNK | Epieriocalyxin A | ERK | epi-Eriocalyxin A | inhibit | Apoptosis | Inhibitor | Bcl-2 |
Inhibitors Related | Rifampicin | TBHQ | 5-Fluorouracil | Acetylcysteine | Guanidine hydrochloride | Lidocaine hydrochloride | Lycopene | Thymidine | Temozolomide | Folic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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