EOAI3402143 NEW
Price | $61 | $147 | $239 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: EOAI3402143 | CAS No.: 1699750-95-2 |
Purity: 98.09% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | EOAI3402143 |
描述 | EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth. |
體外活性 | EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice[2]. Usp9x inhibition by EOAI3402143 treatment reduced 3D colony formation in PANC1 and PDX cell lines, induced rapid apoptosis in MIAPACA2 cells, and associated with reduced Mcl-1 and ITCH protein levels[2]. |
體內(nèi)活性 | EOAI3402143 dose-dependently inhibited Usp9x and Usp24 activity, increased tumor cell apoptosis, and fully blocked or regressed myeloma tumors in mice[3]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 75 mg/mL (148.98 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
關(guān)鍵字 | Inhibitor | Deubiquitinase | DUBs | inhibit | EOAI-3402143 | EOAI3402143 | EOAI 3402143 |
相關(guān)產(chǎn)品 | P22074 | BAY 11-7082 | USP15-IN-1 | N-Ethylmaleimide | DUB-IN-1 | SJB3-019A | USP30 inhibitor 11 | Vialinin A | GRL0617 | Spautin-1 | 6-Thioguanine | USP8-IN-3 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 泛素化化合物庫 | HIF-1化合物庫 | 抑制劑庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Product name | Price | Suppliers | Update time | |
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$61.00/1mg |
VIP5Y
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TargetMol Chemicals Inc.
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2024-11-14 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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