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Postion:Product Catalog >Enpp/Carbonic anhydrase-IN-1
Enpp/Carbonic anhydrase-IN-1
  • Enpp/Carbonic anhydrase-IN-1

Enpp/Carbonic anhydrase-IN-1 NEW

Price $38 $58 $119
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Enpp/Carbonic anhydrase-IN-1 CAS No.: 2883495-35-8
Purity: 100% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameEnpp/Carbonic anhydrase-IN-1
DescriptionEnpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase, exhibiting IC50s of 1.36, 1.35, 3.00, 0.88, and 1.02 μM for NPP1, NPP2, NPP3, CA-II, and CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 also demonstrates selective antiproliferative activity for cancer cells.
In vitroEnpp/Carbonic anhydrase-IN-1 (0-100 μM; ) inhibits cancer cells growth with IC50s of 0.32, 0.40, 0.40, 0.58, 0.87, 0.96 μM for K-562, RPMI-8226, HT-29, SR, COLO 205, SF-539 cells, respectively. Enpp/Carbonic anhydrase-IN-1 (0-2 μM) exhibits low cytotoxic against normal skin fibroblast cells (F180) and normal breast epithelial cells (HME1) with IC50s of > 50 μM. Enpp/Carbonic anhydrase-IN-1 (0.32 μM, 0.64 μM) induces apoptosis in a dose-dependent manner at K-562 cells[1].
StorageShipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (218.7 mM), Sonication and heating to 50℃ are recommended.
KeywordsEnpp/CarbonicanhydraseIN1 | Enpp/Carbonic anhydrase-IN-1
Inhibitors RelatedBenzenesulfonamide | Theophylline monohydrate | Cyclamic acid sodium | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Doxofylline
Related Compound LibrariesBioactive Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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