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Postion:Product Catalog >Elimusertib hydrochloride(1876467-74-1 free base)
Elimusertib hydrochloride(1876467-74-1 free base)
  • Elimusertib hydrochloride(1876467-74-1 free base)

Elimusertib hydrochloride(1876467-74-1 free base) NEW

Price $31 $81 $123
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: Elimusertib hydrochloride(1876467-74-1 free base) Purity: 99.03%
Supply Ability: 10g Release date: 2024/11/14

Product Introduction

Bioactivity

名稱Elimusertib hydrochloride(1876467-74-1 free base)
描述Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
體外活性Elimusertib hydrochloride potently inhibits the proliferation of a broad spectrum of human tumor cell lines (median IC50: 78 nM). BAY-1895344 potently suppresses NSC-32065-induced H2AX phosphorylation (IC50: 36 nM) [1].
體內(nèi)活性In a variety of xenograft models of ovarian and colorectal cancer, Elimusertib hydrochloride shows potent anti-tumor efficacy in monotherapy and causes complete tumor remission in mantle cell lymphoma models [2].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 50 mg/mL (121.39 mM), Sonication and heating are recommended.
H2O : 48 mg/mL (116.53 mM), Sonication is recommended.
關(guān)鍵字BAY1895344 Hydrochloride | BAY 1895344 Hydrochloride | Elimusertib hydrochloride(1876467 74 1 free base) | Elimusertib hydrochloride(1876467-74-1 free base) | Elimusertib hydrochloride(1876467741 free base) | BAY-1895344 Hydrochloride
相關(guān)產(chǎn)品Dactolisib | Berzosertib | Elimusertib | GJ103 sodium salt | Ceralasertib | Schisandrin B
相關(guān)庫經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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