EGFR-IN-7 NEW
Price | $98 | $243 | $396 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: EGFR-IN-7 | CAS No.: 2267329-76-8 |
Purity: 99.64% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | EGFR-IN-7 |
描述 | EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor. |
體外活性 | TQB3804 displayed potent enzymatic activities for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, and EGFRL858R/T790M with IC50 of 0.46, 0.13, 0.26, and 0.19 nM respectively, and has similar enzymatic activity for EGFRWT (IC50 = 1.07) to Osimertinib. It also showed expected anti-proliferative activity in 4 cell lines, Ba/F3 (EGFRd746-750/T790M/C797S), NCI-H1975 (EGFRd746-750/T790M/C797S), PC9 (EGFRd746-750), and A431 (EGFRWT), with IC50 of 26.8, 163, 45, and 147 nM, respectively. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 0.714 mg/mL (1.02 mM), Sonication is recommended. |
關(guān)鍵字 | HER1 | EGFR IN 7 | ErbB-1 | EGFR | Inhibitor | inhibit | Epidermal growth factor receptor | TQB 3804 | TQB-3804 | EGFRIN7 | EGFR-IN-7 |
相關(guān)產(chǎn)品 | Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Afatinib Dimaleate | Erlotinib hydrochloride | Erlotinib | Neratinib | Chalcone | Osimertinib mesylate | Genistein | Khellin | Gefitinib |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抗卵巢癌化合物庫 | 血管生成庫 | 抑制劑庫 | 已知活性化合物庫 | 抗肝癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$2785.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
$75.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-17 | |
$5.00/1KG |
VIP1Y
|
Henan Fengda Chemical Co., Ltd
|
2024-04-09 | |
$98.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-18 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY