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Postion:Product Catalog >API>Digestive system drugs>Gastrointestinal antispasmodic drugs>Drotaverine hydrochloride
Drotaverine hydrochloride
  • Drotaverine hydrochloride

Drotaverine hydrochloride NEW

Price $47 $72 $139
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: Drotaverine hydrochloride CAS No.: 985-12-6
Purity: 99.81% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱Drotaverine hydrochloride
描述Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally related to papaverine
體外活性drotaverine not only relaxed the precontracted tracheal preparations but also decreased mediator-induced contraction.?These effects of drotaverine were concentration dependent, with a significantly higher potency on the KCl-induced response, than on either the histamine or methacholine induced one.?A similar result was noted for nifedipine.?The PDE inhibitor, theophylline, also relaxed the precontracted preparations but was ineffective on the mediator-induced contraction in a physiologically relevant concentration range.
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 25 mg/mL (57.61 mM)
關(guān)鍵字Ca2+ channels | Inhibitor | Drotaverine hydrochloride | Ca channels | inhibit | Drotaverine | Phosphodiesterase (PDE) | Drotaverine Hydrochloride | Calcium Channel
相關(guān)產(chǎn)品Theobromine | Apremilast | Doxofylline
相關(guān)庫神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 抗阿爾茨海默癥化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 神經(jīng)保護(hù)化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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