Doxylamine succinate NEW
| Price | $37 | $50 | $61 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: Doxylamine succinate | CAS No.: 562-10-7 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | Doxylamine succinate |
| 描述 | Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of the gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug also prevents histamine-induced pain and itching of the skin and mucous membranes. |
| 體外活性 | In B6C3F1 mice, the impact of Doxylamine on microsomal enzyme activity and serum thyroid hormone levels was investigated by administering Doxylamine succinate for 7 or 15 days with dietary incorporation at levels of 0, 40, 375, 750, or 1500 ppm, corresponding to the free base form of Doxylamine. Findings reveal that Doxylamine acts as an inducer of hepatic microsomal cytochrome P450 enzymes, consistent with the hypothesis that Doxylamine increases liver enzyme activities involved in T4 metabolism in B6C3F1 mice. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL (257.43 mM) H2O : 100 mg/mL (257.43 mM) |
| 關(guān)鍵字 | B6C3F1 mice | Low toxicity | Liver | inhibit | Subcutaneous infiltration | Doxylamine Succinate | Doxylamine succinate | Inhibitor | Histamine Receptor | Local analgesic | Doxylamine |
| 相關(guān)產(chǎn)品 | Meclizine dihydrochloride | Lidocaine | Famotidine | Alginic acid |
| 相關(guān)庫 | 疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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