Dorzolamide hydrochloride

Product Description

Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.Target: carbonic anhydrase (CA)Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour [1]. Glaucoma was induced in the right eye of adult Wistar rats by episcleral venous occlusion. One experimental group was administered dorzolamide hydrochloride 2%-timolol 0.5% combination eye drops, while the other experimental group was administered dorzolamide hydrochloride2% eye drops. Control groups had surgery without drug administration. Drug application was initiated either 2 weeks before surgery (Group A), from the day of surgery (Group B), 2 weeks after surgery (Group C), or 4 weeks after surgery (Group D). RGCs were labeled by intratectal Fluorogold injections and counted from flat-mount preparations, and IOP was measured using Tonopen. Both dorzolamide-timolol combination and dorzolamide hydrochloride, when applied topically, significantly reduced IOP and improved RGC densities in experimental eyes when compared to control eyes. Earlier initiation, as well as longer duration of drug application, resulted in higher RGC densities [2].Clinical indications: Glaucoma; Ocular hypertensionFDA Approved Date: 1995Toxicity: Dizziness, headache, shortness of breath, slow heartbeat, severe asthma, cardiac arrest

Function

Dorzolomide (trade name Trusopt) is a carbonic anhydrase inhibitor. Dorzolomide hydrochloride is an anti-glaucoma external eye drops. Dorzolomide hydrochloride is used to reduce open-angle glaucoma and ocular hypertension increased intraocular pressure.

Certificate  of  Analysis

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Our Service

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

2.We can provide the reasonable price, high quality products and prompt shipment.

3.We can send the goods to your delivery address directly. It is relatively safe and fast. 

4.Quick and clear response to customers questions, we’ll treat every email and message within 24 hours usually much faster.

5.We can provide you a discount if you place a substantial order with us.

6.Products can be packaged and company logo can be customized according to customer requirements.

Delivery

1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitateyou track the express.



FAQ

Q1: Can i get some samples?
A: Yes, we can supply the sample, but the shipping cost be paid by ourcustomers.

Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosedour bank information. Payment by T/T, Western Union or Paypal.

Q3: How to confirm the Product Quality before placing orders?
A: You can get free samples for some products,you only need to pay theshipping cost or arrange a courier to us and take the samples. You cansend us your product specifications and requests,we will manufacture theproducts according to your requests.

Q4: What's your MOQ?
A: Our MOQ is 1kg. But usually we accept less quantity such as 100g onthe condition that sample charge is 100% paid.

Q5: How about delivery lead time?
A: Delivery lead time: About 3-5 days after payment confirmed. (Chineseholiday not included)

Q6: Do You Ship Over The Weekend?
A: We use EMS, TNT, FEDEX, DHL four kinds of couriers. EMS don't collected parcelsover the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.