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Postion:Product Catalog >API>Antiparasitic drugs>Antimalarial drug>Diminazene Aceturate
Diminazene Aceturate
  • Diminazene Aceturate

Diminazene Aceturate NEW

Price $42
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: Diminazene Aceturate CAS No.: 908-54-3
Purity: 98.78% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱Diminazene Aceturate
描述Diminazene is a trypanocidal agent.
體外活性Administering 7 mg/kg, i.m. of Diminazene aceturate effectively clears parasites from the bloodstream of infected dogs. An initial treatment dose of 3.5 mg/kg of Diminazene aceturate significantly alleviates T. evansi infection in horses and mules, with parasites being eliminated from the peripheral blood within 1-7 days and 1-14 days, respectively.
體內(nèi)活性Transport of [3H] diminazene is substantially inhibited by pentamidine and adenosine, with Ki values of 0.21 μM and 0.25 μM, respectively. Notably, [3H] diminazene accumulates in yeast cells expressing TbAT1 at a rate of 0.0083 pmol/10^7 cells/s when treated with 2.5 μM of the radioactive compound, and this accumulation is completely suppressed by 1 mM of unlabeled Diminazene Aceturate.
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度H2O : 92 mg/mL (178.5 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 1 mg/mL, Sonication is recommended.
關(guān)鍵字Parasite | Inhibitor | Diminazene | Angiotensin-converting Enzyme (ACE) | Diminazene Aceturate | Diminazene diaceturate | inhibit
相關(guān)產(chǎn)品Hydroxychloroquine | Doxycycline
相關(guān)庫(kù)FDA上市及藥典收錄分子庫(kù) | 抗寄生蟲庫(kù) | 經(jīng)典已知活性庫(kù) | 抗衰老化合物庫(kù) | 已知活性化合物庫(kù) | 抗COVID-19化合物庫(kù) | 抗感染化合物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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