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Postion:Product Catalog >API>Diagnostic agents>Medical Imaging Drugs>Diatrizoic Acid
Diatrizoic Acid
  • Diatrizoic Acid

Diatrizoic Acid NEW

Price $113
Package 10g
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: Diatrizoic Acid CAS No.: 117-96-4
Purity: 100% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱Diatrizoic Acid
描述Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.
激酶實(shí)驗(yàn)Radiochemical enzyme assays for COX-1 and COX-2: 10 μL of purified COX-1 (0.7-0.8 μg) or COX-2 (3.0 units, 0.3μg) is activated with 50 μL of cofactor solution [l-epinephrine (1.3 mg/mL), reduced glutathione (0.3 mg/mL), and hematin (1.3 mg/mL) in oxygen-free Tris-HCl buffer (pH 8.0)]. The enzyme solution (60 μL) is added to Ibuprofen solutions or DMSO (20 μL) after [14C]arachidonic acid is added in 0.2 mL eight-strip test tubes and preincubated 10 minutes on ice. Samples are incubated for 15 minutes at 37 °C, after which the reaction is terminated by addition of 10 μL of 2 M HCl and 5 μL of carrier solution (PGE2 and PGF2α, 0.2 μg/mL of each in EtOH). The unmetabolized arachidonic acid is separated from the prostaglandin products by column chromatography and eluted with n-hexane-dioxane-glacial acetic acid (70:30:1). The prostaglandin products are then eluted with EtOAc-MeOH (85:15), and the samples are counted in a Packard scintillation spectrometer. IC50 values are obtained by linear regression analysis.
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (89.59 mM)
關(guān)鍵字Diatrizoic Acid | Inhibitor | inhibit | Apoptosis
相關(guān)產(chǎn)品Stavudine | Sodium 4-phenylbutyrate | Tributyrin
相關(guān)庫ReFRAME 相關(guān)化合物庫 | 藥用輔料化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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