Devapamil NEW

Price	$80	$180	$260
Package	1mg	5mg	10mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-19

Product Details

Product Name: Devapamil	CAS No.: 92302-55-1
Purity: 100%	Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name	Devapamil
Description	Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner.
In vitro	Devapamil (3 μM) reduced L-type calcium currents (ICa) to 16.1 +/- 8.6%, 11 +/- 8.9%, and 9.3 +/- 6% of control, respectively. Intracellular application of the same substances, via the patch pipette filled with 30 μM of devapamil, failed to depress ICa. The quaternary derivatives of the phenylalkylamines (30 microM) were ineffective both when applied extracellularly or intracellularly. It is suggested that phenylalkylamines block ICa in ventricular myocytes by acting on a binding site of the calcium channel molecule located at the outer surface of the cell membrane.[3]
Storage	Shipping with blue ice.
Solubility Information	DMSO : 50 mg/mL (117.76 mM)
Keywords	Devapamil
Inhibitors Related	Nisoldipine \| Nimodipine \| 2,5-Di-tert-butylhydroquinone \| Diltiazem hydrochloride \| Levetiracetam \| L-Ascorbic acid \| Lanthanum(III) chloride heptahydrate \| Ethyl cinnamate \| 1-Octanol \| Otilonium bromide
Related Compound Libraries	Pain-Related Compound Library \| Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Neuroprotective Compound Library \| Bioactive Compounds Library Max \| Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.