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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Nucleotides and their analogs>Cytidine
Cytidine
  • Cytidine

Cytidine NEW

Price $93
Package 10g
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Cytidine CAS No.: 65-46-3
Purity: 99.85% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCytidine
DescriptionCytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.
In vivoD-cycloserine (DCS) facilitates extinction of conditioned freezing to the light CS when no drug pre-exposure has occurred, but pre-exposure to DCS just prior to conditioning disrupted the facilitation of extinction effect in mice. [1] D-cycloserine (DCS) which has a high affinity for the glycine modulatory site in the NMDA receptor complex modulated memory processing in a dose-dependent manner. DCS also facilitates retention in 'senescence-accelerated mice' in which impairment of learning andmemory increases with age. [2] D-cycloserine (DCS) exhibits facilitated extinction of fear but are able to reacquire fear of that conditioned stimulus (CS) in a similar manner as saline-treated control rats. DCS-treated rats exhibits generalized extinction (i.e., they are less fearful of a non-extinguished CS) in comparison to controls. [3] D-cycloserine (DCS), an antimycobacterial agent known to cross the blood-brain barrier, binds with high affinity to this glycine modulatory site, functions as a positive modulator, and facilitates performance of learningtasks in rats. DCS appears to be a potent cognitive enhancer at doses lower than those required for antibacterial activity. [4] D-cycloserine injections (3.25, 15, or 30 mg/kg) before 30 non-reinforced light exposures dose-dependently enhances extinction but does not influence fear-potentiated startle in rats that does not receive extinction training. [5]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 45 mg/mL (185 mM)
DMSO : 60 mg/mL (246.69 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
KeywordsRNA | nucleoside | inhibit | Cytosine b-D-riboside | Cytosine-1-beta-D-ribofuranoside | Nucleoside Antimetabolite/Analog | Cytosine beta-D-riboside | Cytidine | ribofuranose | uridine | Inhibitor | Endogenous Metabolite | Cytosine-1-b-D-ribofuranoside
Inhibitors RelatedSucrose | Stavudine | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin
Related Compound LibrariesTraditional Chinese Medicine Monomer Library | Bioactive Compound Library | Alkaloid Natural Product Library | Microbial Natural Product Library | Natural Product Library for HTS | Human Endogenous Metabolite Library | Anti-Aging Compound Library | Anti-virus Traditional Chinese Medicine Monomer Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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