Cycloastragenol

Product Description

Cycloastragenol, a natural tetracyclic triterpenoid, was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties. IC50 value:Target:In vitro: In the study of Cycloastragenolon the treatment of degenerative diseases, the result showed that first-pass intestinal metabolism of cycloastragenol might occur upon passage through the intestinal epithelium. Cycloastragenol underwent extensive metabolism in rat and human liver microsomes with only 17.4% and 8.2%, respectively, of the starting amount of Cycloastragenol remaining after 30 min of incubation [1]. The present study demonstrates that cycloastragenol stimulates telomerase activity and cell proliferation in human neonatal keratinocytes. In particular, cycloastragenol promotes scratch wound closure of human neonatal keratinocyte monolayers in vitro [3]. In vivo: Rats were treated with Cycloastragenol (40 mg·kg- 1·d- 1) for 7 days to induce hepatic microsomal enzyme. The result showed that compared with the control, cycloastragenol obviously activated CYP2E1, and remarkably inhibited CYP3A4 [2].

Application

1. Enhancing immunity, protecting liver, diuretic, anti-aging, anti-stress, bring high blood pressure down and wider antibacterial.

2. Helping the body to expand the blood vesseland and the coronary artery.

3.It is helpful to prevent the descend of the amount of white blood cell, haematoblast, reticulocyte, megakaryocyte.

4. It can lengthen the life of the cells and delay the consenescence.

5. Treating diseases of Spleen and stomach, loss of appetite, loose stools and body weary.

Certificate of Analysis

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Our Service

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

2.We can provide the reasonable price, high quality products and prompt shipment.

3.We can send the goods to your delivery address directly. It is relatively safe and fast. 

4.Quick and clear response to customers questions, we’ll treat every email and message within 24 hours usually much faster.

5.We can provide you a discount if you place a substantial order with us.

6.Products can be packaged and company logo can be customized according to customer requirements.

Delivery

1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitateyou track the express.



FAQ

Q1: Can i get some samples?
A: Yes, we can supply the sample, but the shipping cost be paid by ourcustomers.

Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosedour bank information. Payment by T/T, Western Union or Paypal.

Q3: How to confirm the Product Quality before placing orders?
A: You can get free samples for some products,you only need to pay theshipping cost or arrange a courier to us and take the samples. You cansend us your product specifications and requests,we will manufacture theproducts according to your requests.

Q4: What's your MOQ?
A: Our MOQ is 1kg. But usually we accept less quantity such as 100g onthe condition that sample charge is 100% paid.

Q5: How about delivery lead time?
A: Delivery lead time: About 3-5 days after payment confirmed. (Chineseholiday not included)

Q6: Do You Ship Over The Weekend?
A: We use EMS, TNT, FEDEX, DHL four kinds of couriers. EMS don't collected parcelsover the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.