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Postion:Product Catalog >CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE
CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE
  • CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE
  • CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE

CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE NEW

Price $6 $5 $1
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: CREATINE PHAMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE CAS No.: 1955-67-5
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Name: Sun

1. Product information

Names

Nameglutamine hydroxamate
SynonymMore Synonyms

 L-GlutaMic acid γ-MonohydroxaMate Biological Activity

DescriptionL-Glutamic γ-monohydroxamate is an antitumor agent, inhibits cell proliferation. L-Glutamic γ-monohydroxamate selectively inhibits the uptake of L-histidine into microvascular endothelial cell. L-Glutamic γ-monohydroxamate, as a vanadium ligand, activates glucose uptake and metabolism, thus decreases the blood glucose levels in vivo[1][2][3].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease
References

[1]. Vila J, et al. In vitro and in vivo anti-tumor activity of L-glutamic acid gamma-monohydroxamate against L1210 leukemia and B16 melanoma. Int J Cancer. 1990 Apr 15;45(4):737-43.

[2]. Sakurai E, et al. Stereoselective transport of histidine in rat lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1192-7.

[3]. Goldwaser I, et al. L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo. J Biol Chem. 1999 Sep 10;274(37):26617-24.

 Chemical & Physical Properties

Density1.432g/cm3
Boiling Point553.6oC at 760mmHg
Molecular FormulaC5H10N2O4
Molecular Weight162.14400
Flash Point288.6oC
Exact Mass162.06400
PSA116.14000
LogP0.22450
Vapour Pressure1.46E-14mmHg at 25°C
Index of Refraction1.538
Storage condition-20°C

 MSDS

L-GlutaMic acid γ-MonohydroxaMate MSDS(Chinese)

 Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2928000090

 Synthetic Route

Previous 1/3 Next
Article illustration

L-(+)Sodium glu...

CAS#:142-47-2

~%

Article illustration

L-GlutaMic acid...

CAS#:1955-67-5

Literature: Yamamoto, Sachiko; Wakayama, Mamoru; Tachiki, Takashi Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 2 p. 545 - 552
Article illustration

H-Glu(Gln-OH)-OH

CAS#:10148-81-9

~%

Article illustration

L-GlutaMic acid...

CAS#:1955-67-5

Literature: Imaoka, Masashi; Yano, Shigekazu; Okumura, Masashi; Hibi, Takao; Wakayama, Mamoru Bioscience, Biotechnology and Biochemistry, 2010 , vol. 74, # 9 p. 1936 - 1939
Article illustration

H-Glu(OEt)-OH

CAS#:1119-33-1

~%

Article illustration

L-GlutaMic acid...

CAS#:1955-67-5

Literature: Roper; McIlwain Biochemical Journal, 1948 , vol. 42, p. 488

 Precursor & DownStream

Precursor  7

Previous 1/2 Next

  • Article illustration CAS#:142-47-2
    L-(+)Sodium glu...

  • Article illustration CAS#:10148-81-9
    H-Glu(Gln-OH)-OH

  • Article illustration CAS#:1119-33-1
    H-Glu(OEt)-OH

  • Article illustration CAS#:3183-72-0
    N-γ-L-glutamyl-...

DownStream  1



  • Article illustration CAS#:56-86-0
    L-glutamic acid

 Customs

HS Code2928000090
Summary2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles19

More Articles
Cell differentiation of Proteus mirabilis is initiated by glutamine, a specific chemoattractant for swarming cells.

Mol. Microbiol. 8(1) , 53-60, (1993)

Swarming by Proteus mirabilis involves differentiation of typical short vegetative rods into filamentous hyperflagellated swarm cells which undergo cycles of rapid and co-ordinated population migratio...

Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.

Eur. J. Biochem. 271(21) , 4204-12, (2004)

Cytidine 5'-triphosphate (CTP) synthase catalyses the ATP-dependent formation of CTP from uridine 5'-triphosphate using either NH(3) or l-glutamine as the nitrogen source. The hydrolysis of glutamine ...

Effect of epidermal growth factor on glutamine metabolic enzymes in small intestine and skeletal muscle of parenterally fed rats.

Nutrition 13(7-8) , 652-5, (1997)

Exogenous epidermal growth factor (EGF) markedly increases the in vivo uptake of glutamine by small intestine during total parenteral nutrition (TPN). Since glutamine is the major oxidative fuel for t...

 Synonyms

(4S)-4-Amino-4-carboxybutanehydroxamic acid
(2S)-5-amino-2-(hydroxyamino)-5-keto-valeric acid
N5-Hydroxy-L-glutamine
(S)-4-Amino-4-carboxybutanehydroximic acid
3-[2-Oxo-2-(hydroxyamino)ethyl]alanine
(2S)-2-Amino-5-oxo-5-(hydroxyamino)pentanoic acid
AMINO ACID HYDROXAMATES L-GLUTAMIC ACID γ-MONOHYDROXAMATE
L-GlutaMic acid γ-MonohydroxaMate



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137





Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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