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Postion:Product Catalog >COH34
COH34
  • COH34

COH34 NEW

Price $135 $289 $455
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: COH34 CAS No.: 906439-72-3
Purity: 98.21% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱COH34
描述COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
體外活性COH34 potently inhibits PARP inhibitor-resistant cancer cells[1].
體內活性COH34 shows antitumor activity in xenograft mouse cancer models[1].
存儲條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 15 mg/mL (51.1 mM), Sonication is recommended.
關鍵字COH-34 | COH 34 | COH34

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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2024-11-11
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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