CNQX NEW
| Price | $41 | $57 | $124 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-04 |
Product Details
| Product Name: CNQX | CAS No.: 115066-14-3 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/04 |
Product Introduction
Bioactivity
| 名稱 | CNQX |
| 描述 | CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively) |
| 體外活性 | In rat hippocampal slices bathed in Mg2+-free medium 10 microM CNQX reversibly blocks responses to alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), quisqualate and kainate but not NMDA. The synaptic response evoked by low frequency stimulation of Schaffer collateral-commissural fibres in 1 mM Mg2+-containing medium is completely blocked by this concentration of CNQX. In contrast the synaptic response evoked in Mg2+-free medium is not fully blocked by CNQX[1]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 20 mg/ml (86.15 mM), Sonication is recommended. |
| 關鍵字 | fear-potentiated | startle | AMPA | FG 9065 | non-NMDA | iGluR | kainate | CNQX | inhibit | Inhibitor | FG-9065 | Ionotropic glutamate receptors |
| 相關產(chǎn)品 | Mephenesin | L-Glutamic acid | glycine | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Linalool | O-Phospho-L-serine |
| 相關庫 | 經(jīng)典已知活性庫 | 神經(jīng)退行性疾病化合物庫 | 抗阿爾茨海默癥化合物庫 | 膜蛋白靶向化合物庫 | ReFRAME 相關化合物庫 | 神經(jīng)保護化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫 | 離子通道庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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