成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >CMS-121
CMS-121
  • CMS-121

CMS-121 NEW

Price $37 $57 $107
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: CMS-121 CAS No.: 1353224-53-9
Purity: 98.71% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱CMS-121
描述CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.
體外活性CMS-121 can increase acetyl-CoA in cells. CMS-121 (1 μM; 4 hours; HT22 cells) treatment also increases the phosphorylation of ACC1 at serine 79.[1].
體內(nèi)活性CMS-121 preserves mitochondrial homeostasis by regulating acetyl-coenzyme A (acetyl-CoA) metabolism. CMS-121 (~20 mg/kg; p.o; daily; for 4 months; female SAMP8 mice) treatment decreases cognitive decline and metabolic and transcriptional markers of aging in the brain when administered to rapidly aging SAMP8 mice. [1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (171.14 mM), Sonication is recommended.
關(guān)鍵字ACC, Acetyl Coenzyme A Carboxylase | CMS 121 | disease | neuroprotective | inhibit | anti-inflammatory | mitochondrial | Alzheimer's | antioxidative | acetylation | Inhibitor | H3K9 | CMS-121 | Acetyl-CoA Carboxylase | dementia | ACC1
相關(guān)產(chǎn)品ND-646 | Olumacostat Glasaretil | PF-05175157 | Haloxyfop | CP-640186 hydrochloride | Firsocostat | PF-05221304 | CP-640186 | Quizalofop-P | Moiramide B | TOFA | Tralkoxydim
相關(guān)庫經(jīng)典已知活性庫 | 抗肥胖化合物庫 | 神經(jīng)保護化合物庫 | 抑制劑庫 | 口服活性化合物庫 | 代謝化合物庫 | 脂代謝化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 氧化還原化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

  • CAS:916482-17-2

    $138.00 / 1mg

  • CAS:432529-82-3

    $36.00 / 5mg

  • CAS:2099681-31-7

    $350.00 / 1mg

Recommended supplier

Product name Price   Suppliers Update time
$82.00/2mg
VIP3Y
TargetMol Chemicals Inc.
2024-10-23
$0.00/20kg
VIP2Y
Wuhan Haorong Biotechnology Co.,Ltd
2023-07-22
$1980.00/50mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$0.00/1kg
VIP3Y
Wuhan Senwayer Century Chemical Co.,Ltd
2023-04-20
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY