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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Quinoline compounds>Cloquintocet-mexyl
Cloquintocet-mexyl
  • Cloquintocet-mexyl
  • Cloquintocet-mexyl
  • Cloquintocet-mexyl

Cloquintocet-mexyl NEW

Price $30
Package 1g
Min. Order: 1g
Supply Ability: 2000kg
Update Time: 2024-12-23

Product Details

Product Name: Cloquintocet-mexyl CAS No.: 99607-70-2
Min. Order: 1g Purity: 98%
Supply Ability: 2000kg Release date: 2024/12/23

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Cloquintocet-mexyl Chemical Properties
Melting point 69°
Boiling point 448.4±30.0 °C(Predicted)
density 1.163±0.06 g/cm3(Predicted)
vapor pressure 0-54.4Pa at 25-185.9℃
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka1.94±0.29(Predicted)
form neat
color White to Off-White
Merck 14,2401
Stability:Stable. Incompatible with strong oxidizing agents.
LogP5.2-5.24 at 25℃ and pH5-9.1
Surface tension56.8-57.2mN/m at 590μg/L and 20℃
Dissociation constant3.55 at 20℃
CAS DataBase Reference99607-70-2(CAS DataBase Reference)
EPA Substance Registry SystemCloquintocet-mexyl (99607-70-2)
Cloquintocet-mexyl Usage And Synthesis
DescriptionCloquintocet-mexyl is a colourless crystalline herbicide safener. It is categorized as Class III toxin.
Chemical Propertiesbeige solid
UsesCloquintocet-mexyl is used as a herbicide.
UsesCloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired.
DefinitionChEBI: Heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate is a member of the class of quinolines that is quinoline which is substituted by a chloro group at position 5 and by a 2-[(heptan-2-yl)oxy]-2-oxoethoxy group at position 8. It is an aromatic ether, an organochlorine compound, a member of quinolines and a carboxylic ester.
Agricultural UsesCloquintocet-mexyl is a safener that can be used in conjunction with various herbicides to reduce phytotoxicity to crops. Though effective as a safener, the manufacture, storage, and use of cloquintocet-mexyl containing products can present challenges owing to its sensitivity to water and its low melting temperature (i.e., 61-69° C. for technical material). When products containing cloquintocet-mexyl are prepared, stored, or used in the presence of water, cloquin tocet-mexyl can undergo hydrolysis to form cloquintocet acid, and/or form a needle-shaped, crystalline hydrate that can, lead to clogged spray nozzles during spray applications and/or possibly increased levels of crop phytotoxicity.
CarcinogenicityIn accordance with the EPA Proposed EPA Weight-of-the-Evidence Categories, August 1999, the HIARC classified cloquintocet-mexyl as "not likely to be a human carcinogen." Carcinogenicity studies in rats and mice did not show increased incidence of spontaneous tumor formation. With negative mutagenic test battery, it is suggested that cloquintocet-mexyl (CGA 185072) is not likely to be a human carcinogen.
MetabolismMetabolism studies in rats indicated that approximately 40% of the administered dose of cloquintocet-mexyl was absorbed through the gastrointestinal tract and subsequently excreted via the urine. Fecal excretion accounted for approximately 60% of the administered dose. The chemical was rapidly eliminated (more than 80% of the administered dose) via feces and urine within 48 hours post-dosing. Sex, dosing regime, and dose levels had little effect on the excretion pattern. Excretion patterns were similar between the biliary cannulated and non-cannulated animals indicating that there was no enterohepatic circulation of the chemical. Three days after administration, tissue radioactivity accounted for less than 0.3% of the administered dose (or was non-detectable) and was not detectable in the expired air. At day three post-dosing, most tissue residues of radioactivity were below the limit of detection. The major metabolic pathway of cloquintocet-mexyl was ester hydrolysis to yield 5-chloro-8-quinolinoxy acetic acid, the major metabolite in the fecal and urinary pools.
Toxicity evaluationCloquintocet-mexyl has a low order of acute oral, dermal, and inhalation toxicity. It is slightly irritating to the eyes and non-irritating to the skin. Cloquintocet-mexyl is a skin sensitizer. The chemical is not genotoxic and is not a reproductive and developmental toxicant. There is no evidence of neurotoxicity in the available studies. Cloquintocet-mexyl is classified as “not likely to be a human carcinogen.” The main metabolite for cloquintocet-mexyl is 5-chloro-8-quin-linoxyacetic acid, and testing on the metabolite is part of the toxicology database for cloquintocet-mexyl.

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Company Profile Introduction

Hebei Hongtan Technology Co., Ltd. was established in 2018. In 2019, the Ministry of Foreign Trade was established. The team has 10 members and has invested $300,000 in product development. Our goal is to make everyone can use inexpensive beauty products, the company's products have passed the CE certification, the main products are slimming peptide, anti-wrinkle peptide, melanin peptide, etc., reliable quality, inexpensive.

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