Clopidogrel hydrogen sulfate NEW
Price | $30 | $40 | $50 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-05 |
Product Details
Product Name: Clopidogrel hydrogen sulfate | CAS No.: 120202-66-6 |
Purity: 99.57% | Supply Ability: 10g |
Release date: 2024/11/05 |
Product Introduction
Bioactivity
名稱 | Clopidogrel hydrogen sulfate |
描述 | Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation. |
體外活性 | In a rat model of ulcer margins, daily administration of Clopidogrel (2 mg and 10 mg/kg) significantly reduced the proliferation of gastric epithelial cells induced by ulcers, as well as the expression of the EGF receptor and phosphorylated extracellular signal-regulated kinase. In rats with congestive heart failure, Clopidogrel enhanced the phosphorylation of AKT and eNOS, thereby improving vascular endothelial function and the bioavailability of nitric oxide. |
體內(nèi)活性 | In RGM-1 cells, Clopidogrel (1 μM) inhibits the epidermal growth factor-induced activation of epidermal growth factor receptor, PERK expression, and cellular proliferation. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 55 mg/mL (130.98 mM) |
關(guān)鍵字 | Inhibitor | Antiplatelet | Clopidogrel hydrogen | Clopidogrel Bisulfate | P2Y Receptor | platelet | Clopidogrel hydrogen sulfate | CYP2C19 | CYPs | clot | antithrombotic | Clopidogrel hydrogen Sulfate | inhibit | aggregation | Cytochrome P450 | blood | CYP2B6 |
相關(guān)產(chǎn)品 | Tebuconazole | 1-Ethynylnaphthalene | Apigenin | Gemfibrozil | Fenofibrate | 1-Aminobenzotriazole | Uridine-5'-diphosphate disodium salt | Naringin | Naringenin | Tauroursodeoxycholate |
相關(guān)庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | EMA 上市藥物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抗癌上市藥物庫 | FDA 上市藥物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36?Washington?Street, Wellesley?Hills
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