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Postion:Product Catalog >API>Circulatory system drugs>Lipid regulating drugs>Clinofibrate
Clinofibrate
  • Clinofibrate

Clinofibrate NEW

Price $39 $55 $113
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Clinofibrate CAS No.: 30299-08-2
Purity: 99.84% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameClinofibrate
DescriptionClinofibrate (Lipoclin)(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol and triacylglyceride levels in the blood.
In vitroIn the treatment of arteriosclerosis in rats, Clinofibrate significantly reduces high plasma cholesterol levels. When used in CAPD patients, it effectively decreases very low-density lipoprotein levels. Typically, Clinofibrate (600 mg/daily) reduces serum triglycerides by 36% and very low-density lipoprotein triglycerides by 48%. Additionally, it ameliorates abnormalities in low-density and high-density lipoprotein compositions, markedly increasing the content of high-density lipoprotein cholesterol.
In vivoClinofibrate, with an IC50 of 40 μM, acts on the activity of human liver 3α-hydroxysteroid dehydrogenase.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 87 mg/mL (185.7 mM)
Ethanol : 87 mg/mL (185.7 mM)
KeywordsS 8527 | Clinofibrate | HMG-CoA Reductase (HMGCR) | Autophagy | inhibit | Inhibitor | S8527
Inhibitors RelatedHydroxychloroquine | Guanidine hydrochloride
Related Compound LibrariesBioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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