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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiviral drugs>Clevudine
Clevudine
  • Clevudine
  • Clevudine
  • Clevudine
  • Clevudine
  • Clevudine

Clevudine

Price Get Latest Price
Package 1kg 25kg 100kg
Min. Order: 1kg
Supply Ability: 20tons
Update Time: 2024-11-08

Product Details

Product Name: Clevudine CAS No.: 163252-36-6
Min. Order: 1kg Purity: 99%
Supply Ability: 20tons Release date: 2024/11/08
Identification
NameClevudine
Other names

Clevudine

163252-36-6

L-FMAU

Levovir

1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS number163252-36-6
Molecular FormulaC10H13FN2O5
Molecular Weight260.22
EINECS200-001-2
Chemical and Physical Properties
AppearanceWhite Powder

Melting point

184-185°
Boiling point/
PackageG/KG/MT
HS Code29349990
Application
Drug Indication/Application/UseClevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate.

The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued.

 
Formulations/PreparationsOral Tablet
Handling and Storage
Safety and HazardsThe Shanghai Research Institute of Chemical industry testing center identification conclusion :1 No hazard identification, 2 The substance is not subject to IATA DGR, 3 Nonpacking requirements.
Handling and Storage2-8°C
Sample packageDouble plastic bags inside, aluminum foil bag outside 
Commercial packageDouble plastic bags inside,5kg, 10kg, and 25kg fiber drum outside.
Shipping groupIII
Sales restrictionNo
OriginChina
Technnical support 
Clevudine, STD Datasheet
Clevudine, MSDS
Clevudine, COA
Clevudine, Transport Certificate
Yes
Yes
Yes
Yes

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Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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