CFTR corrector 4 NEW
Price | $68 | $178 | $278 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: CFTR corrector 4 | CAS No.: 1918142-34-3 |
Purity: 98.43% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | CFTR corrector 4 |
描述 | CFTR corrector 4 is a potent and orally available transmembrane conductance regulator (CFTR) for cystic fibrosis and is a potent (R,R) type active enantiomer. CFTR corrector 4 increases CFTR levels on the cell surface and is a potential compound for the study of cystic fibrosis. |
體外活性 | CFTR corrector 4 (Compound 13) possesses high potency and efficacy with an EC50 of 0.028 μM in HBE-TECC assay that assesses the CFTR function. CFTR corrector 4 is tested its potency and efficacy in human bronchial epithelial (HBE) cells with an EC50 value of 130 nM in the cell surface expression (CSE-HRP) assay.[1] |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (92.67 mM) |
關(guān)鍵字 | CFTR corrector 4 |
相關(guān)產(chǎn)品 | Glibenclamide | CFTR corrector 8 | Lumacaftor | VRT-532 | GLPG1837 | Glucosamine | Ataluren | DNDS | BPO-27 racemate | Ivacaftor |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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