CDDO-dhTFEA NEW
| Price | $64 | $93 | $155 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: CDDO-dhTFEA | CAS No.: 1191265-33-4 |
| Purity: 98.88% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | CDDO-dhTFEA |
| 描述 | CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD). |
| 體內(nèi)活性 | CDDO-dhTFEA restores hypertension, increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis, and inflammation in the chronic kidney disease rats [2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL (174.00 mM), Sonication is recommended. |
| 關(guān)鍵字 | RTA dh 404 | Nuclear factor-κB | Inhibitor | RTA dh-404 | CDDO-dhTFEA | CDDOdhTFEA | Keap1-Nrf2 | RTA dh404 | Nuclear factor-kappaB | CDDO dhTFEA | inhibit | NF-κB |
| 相關(guān)產(chǎn)品 | TBHQ | Diethylmaleate | Resveratrol | Curcumin | Glucosamine | sodium lauroyl-α-hydroxyethyl sulfonate | Lidocaine hydrochloride | 5-Aminosalicylic Acid | Indole-3-carbinol | Diallyl disulfide |
| 相關(guān)庫 | NF-κB 通路分子庫 | 經(jīng)典已知活性庫 | 抗肥胖化合物庫 | 抑制劑庫 | PPI抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌活性化合物庫 | 轉(zhuǎn)錄因子庫 | 抗高血壓化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $96.00/1mg |
VIP5Y
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TargetMol Chemicals Inc.
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2024-11-12 | |
| $64.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-18 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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