CD16a Protein, Human, Recombinant (F176V, His) NEW
| Price | $2240 |
| Package | 500μg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: CD16a Protein, Human, Recombinant (F176V, His) | Purity: SDS-PAGE: 96.7%; SEC-HPLC: 99.0% |
| Supply Ability: 10g | Release date: 2024/11/18 |
Product Introduction
Bioactivity
| Name | CD16a Protein, Human, Recombinant (F176V, His) |
| Description | The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells._x000D_ CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the Fc portion of various antibodies. CD16a / FCGR3A also has a broader function. CD16a / FCGR3A is directly involved in the lysis of some virus-infected cells and tumor cells by NK cells, independent of antibody binding. Cross-linking of CD16a / FCGR3A on NK cells resulted in increased intracellular Ca2+ levels and a cascade of biochemical events similar to those activated by the T cell receptor. CD16a / FCGR3A on human NK cells is a lysis receptor that mediates the direct killing of some virus infected and tumor cells, independent of antibody ligation. |
| Storage | Shipping with blue ice. |
| Keywords | IMD-20 | IMD 20 | IGFR-3 | IGFR 3 | FCR10 | FCR 10 | FCGR-3 | FCGR 3 | FCG-3 | FCG 3 | Fc gamma RIIIa | Fc fragment of IgG, low affinity IIIa, receptor | CD-16 | CD 16 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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