Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, ethyl ester NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 200kg |
Update Time: | 2023-11-01 |
Product Details
Product Name: Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, ethyl ester | CAS No.: 1869118-24-0 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 200kg | Release date: 2023/11/01 |
Carbamic acid, N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]-, ethyl ester
It is a chemical compound with the molecular formula C16H16N4O4S and the CAS number 1869118-24-0. It has a density of 1.43 g/cm3 and a pKa of 9.45.
It is a JAK1 inhibitor and an intermediate for the synthesis of upadacitinib, a drug for the treatment of various autoimmune and inflammatory diseases.
Upadacitinib has shown good efficacy in clinical trials for rheumatoid arthritis, psoriatic arthritis, psoriasis, ankylosing spondylitis, ulcerative colitis and others.
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