Canertinib dihydrochloride NEW
| Price | $48 | $68 |
| Package | 10mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Canertinib dihydrochloride | CAS No.: 289499-45-2 |
| Purity: 99.23% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Canertinib dihydrochloride |
| Description | Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. |
| Kinase Assay | Kinase inhibition: Cediranib is dissolved in DMSO at a concentration of 10 mM. All enzyme assays are run at, or just below, the respective Km for ATP (0.2 - 30 μM). The inhibitory activity of Cediranib is determined against a range of recombinant tyrosine kinases [KDR, Flt-1, Flt-4, c-Kit, PDGFRα, PDGFRβ, CSF-1R, Flt-3, FGFR1, Src, Abl, epidermal growth factor receptor (EGFR), ErbB2, Aurora A, and Aurora B] using ELISA. Selectivity versus CDK2 and CDK4 serine/threonine kinases is examined using scintillation proximity assays with a retinoblastoma substrate and [γ-sup>33P]ATP. Activity of Cediranib is compared to MAPK kinase (MEK), which shows dual specificity. It is determined using a MAPK substrate, [γ-33P]ATP, and paper capture/scintillation counting. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55.9 mg/mL (100 mM) |
| Keywords | ErbB-1 | PD 183805 | PD 183805 Dihydrochloride | Orthopoxvirus | PD-183805 | EGFR | Canertinib dihydrochloride | CI 1033 Dihydrochloride | PD183805 Dihydrochloride | PD183805 | CI1033 Dihydrochloride | Epidermal growth factor receptor | CI 1033 | PD-183805 Dihydrochloride | Inhibitor | CI1033 | inhibit | HER1 | CI-1033 | Canertinib Dihydrochloride | CI-1033 Dihydrochloride |
| Inhibitors Related | Osimertinib | Lapatinib | Erlotinib | Gefitinib |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Drug Repurposing Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1kg |
VIP5Y
|
Hebei Yanxi Chemical Co., Ltd.
|
2023-10-08 | |
| $0.00/1g |
Beijing Mesochem Technology Co.,Ltd
|
2022-02-21 | ||
| $19.00/1Kg/Bag |
Hong Kong Tiansheng New Material Trading Co., Ltd
|
2021-12-28 | ||
| $6.00/1g |
Qiuxian Baitai New Material Co., LTD
|
2021-11-22 | ||
| $1.10/1g |
VIP4Y
|
Dideu Industries Group Limited
|
2021-07-05 | |
| $15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-06-26 | ||
| $8.00/1kg |
VIP7Y
|
Career Henan Chemical Co
|
2018-12-24 | |
| $23.00/1KG |
Hong Kong Tiansheng New Material Trading Co., Ltd
|
2021-12-16 | ||
| $8.00/1kg |
VIP7Y
|
Career Henan Chemical Co
|
2018-12-24 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY