cAC 253 acetate NEW
Price | $195 | $447 | $659 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: cAC 253 acetate | Purity: 99.99% |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | cAC 253 acetate |
Description | cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM. |
In vitro | cAC 253 acetate (5-20 μM) antagonizes adrenomedullin-stimulated cAMP production at micromolar concentrations[1]. cAC 253 acetate (5-10 μM) blocks increases in intracellular Ca2+, activation of protein kinase A, MAPK, Akt, cFos, and cell death, which occur upon AMY3 activation with hAmylin, Aβ1-42, or their co-application[2]. cAC 253 acetate (10 nM) blocks Aβ1-42-induced electrophysiological effects[3]. |
Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | TP 2135 | TP2135 Free base | cAC 253 Acetate | cAC-253 Acetate | cAC253 Acetate | TP2135 | TP-2135 |
Inhibitors Related | AC 187 Acetate | Amylin, amide, rat acetate(124447-81-0,free base) |
Related Compound Libraries | Peptide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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